Saturday, August 24, 2013

DNA from our mother's influences the aging process

Scientists say that the process through which we age is determined not only by the changes we go through in our lifetime, but also by the genes we get from our mothers.

A new research from from Karolinska Institute and the Max Planck Institute for Biology of Aging, say's that the process of aging is dependent of the power house of the cell, i.e the Mitochondria (The mitochondrion is located within the cell and is responsible for producing the cell's supply of Adenosine 5'-triphosphate (ATP) - a source of chemical energy) 

According to the professor at the Karolinska Institute and principal investigator at the Max Planck Institute for Biology of Aging, Nils-Göran Larsson - "The mitochondria contains their own DNA, which changes more than the DNA in the nucleus, and this has a significant impact on the aging process" also "Many mutations in the mitochondria gradually disable the cell's energy production."

So basically, "a mutated DNA speeds up the aging process."
Mitochondrial DNA (mDNA) damage can build up over a person's lifetime, according to the researchers. But this latest study has found that mitochondrial DNA damage can actually be passed on from our mothers.

This research was performed on a series of inbred mice, and through MRI scanning the scientist were able to detect the amount of mutated DNA's which lead to speed up the aging process in mice.

So, if we inherit more mutated mDNA (Mitochondria DNA) from our mothers we age more quickly.

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